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January 19, 2023
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The clinical trial of the nasal vaccine for Alzheimer's disease launched by Brigham and Women's Hospital.
The first clinical trial for Alzheimer's disease vaccine has just started.
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The 20-year long research journey has paved the road to initiate the first human trial to assess the safety and efficacy of a nasal vaccine that is intended to prevent and slow down the progression of Alzheimer's disease (A. The clinical trial involves 16 symptomatic AD subjects between the ages of 60-85. Howard L. Weiner, MD, co-director of the Ann Romney Center for Neurologic Diseases at the Brigham, gathered preclinical evidence of this nasal vaccine's potential to prevent and treat AD - using the immune system. This vaccine utilizes Protolin, an investigational agent that is derived from bacteria. Protolin can modulate the immune system, activating white blood cells in the lymph nodes to migrate to the brain and start to clear amyloid plaques -- extracellular deposits of amyloid beta protein that are one of the hallmarks of AD.
Source: BWH
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The 20-year long research journey has paved the road to initiate the first human trial to assess the safety and efficacy of a nasal vaccine that is intended to prevent and slow down the progression of Alzheimer's disease (A. The clinical trial involves 16 symptomatic AD subjects between the ages of 60-85. Howard L. Weiner, MD, co-director of the Ann Romney Center for Neurologic Diseases at the Brigham, gathered preclinical evidence of this nasal vaccine's potential to prevent and treat AD - using the immune system. This vaccine utilizes Protolin, an investigational agent that is derived from bacteria. Protolin can modulate the immune system, activating white blood cells in the lymph nodes to migrate to the brain and start to clear amyloid plaques -- extracellular deposits of amyloid beta protein that are one of the hallmarks of AD.
Source: BWH
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Dr. Ana Baroni MD. Ph.D.
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Ana has over 20 years of consultancy experience in longevity, regenerative and precision medicine. She has a multifaceted understanding of genomics, molecular biology, clinical biochemistry, nutrition, aging markers, hormones and physical training. This background allows her to bridge the gap between longevity basic sciences and evidence-based real interventions, putting them into the clinic, to enhance the healthy aging of people. She is co-founder of Origen.life, and Longevityzone. Board member at Breath of Health, BioOx and American Board of Clinical Nutrition. She is Director of International Medical Education of the American College of Integrative Medicine, Professor in IL3 Master of Longevity at Barcelona University and Professor of Nutrigenomics in Nutrition Grade in UNIR University.
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