Exploring the Immune System As A Hallmark Of Aging (Webinar with Vijay Vaswani follow-up + recording)

The HealthyLongevity.guide is proud to announce another successful webinar. In this webinar, our speaker Vijay Vaswani, a co-founder & CEO at Omniscope, covered some interesting points about the immune system, how it impacts the aging process, and its influence on longevity. The webinar was hosted by HealthyLongevity.guide content creators Agnieszka Szmitkowska, Ph.D., and Ehab Naim, MBA.

At the beginning of the webinar, Vijay explained how aging is viewed as a disease. He highlighted that the mortality rate increases as people advance in age. He mentioned that infections could contribute to earlier and higher mortality rates than cancer, heart diseases, dementia, and stroke. He discussed that chest infection, at a young age, causes high mortality rates, then this rate drops after the first decade of life up to the sixth, where the rate starts to increase exponentially with age. He attributed this phenomenon to the diminished ability of the immune system to detect and fight diseases. Vijay explained that T cells receptors diversity enables the body's defense system to detect and recognize numerous foreign agents, including viruses, microbes, cancer cells, and therapeutics. The latter induces a specific immune response defined by the adaptive immune receptor repertoire. Vijay then discussed how the aging process is responsible for disrupting this diversity, making the person more liable to the impact of the abovementioned foreign agents.

Vaswani highlighted the potential of vaccination in rejuvenating immune cells' repertoire and diminishing age-related risks. He showed that unvaccinated individuals tend to die earlier and at higher rates from infections than vaccinated people. He discussed an example of COVID-19 vaccination and showed how vaccines boost T cells post-vaccination. Vijay discussed the cytomegalovirus (CMV) and how It is one of the most common infections affecting 60-90% of adults. He mentioned that CMV reduces the immune system’s ability to respond to other diseases. He revealed that the latter is driven by CMV’s capacity to reduce the immune repertoire diversity.

Vijay discussed the importance of understanding the immune system to match age therapies. He mentioned several bodily functions affected by aging, like telomere shortening, senescence, and mitochondrial function. He continued explaining some anti-aging treatments, like senolytics, vaccines, immunotherapy, and other technologies. Then, Vaswani presented some immune health technology solutions provided by Omniscope. He mentioned the OS-T, a T cell sequencing platform that can sequence up to 1 million T cells per clinical sample. He also presented Ominscope’s Biomarker tracker and Journaling applications. These apps allow gathering additional data to enhance immune repertoire analysis. He revealed that the applications work by collecting historical and real-time biomarker data via wearables, and the phone app can be used to collect qualitative data via journaling.

Be sure to check the recording of this webinar by visiting the HealthyLongevity.guide, where you can find much more information you can utilize to improve the longevity of your clients. Stay tuned for our next webinar with Dr. Jay T. Wiles on August 18, 9 AM PT. The upcoming webinar will discuss Biometrics and Stress: Using Data to Enhance Self-awareness and Self-Regulation.

Some useful resources

https://www.omniscope.ai/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291468/

https://www.nature.com/articles/s41577-021-00646-4

https://www.nature.com/articles/s41590-021-00927-z

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