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Men have reduced pre-existing immunity to influenza
The pre-vaccination immunity was constant with age in women but decreased significantly for men.
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The World Health Organization estimates that 290,000 to 650,000 people die of flu-related causes every year worldwide. Nine in every ten deaths associated with influenza in the USA occur in adults older than 65 years. A study evaluated 90 individuals over 75 years that received 433 doses of influenza vaccine over at least four seasons. The goal was to determine the influence of age and sex on the effect of vaccination and levels of pre-existing immunity to influenza. The study compared the levels of pre- and post-vaccination immune response. The pre-vaccination immunity was constant with age in women but decreased significantly for men. Since the pre-vaccination titers were associated with post-vaccine results, pre-existing immunity in older adults is crucial. One of the ways to achieve it is a cumulative annual vaccination.
Source: nature.com, ncbi.com
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The World Health Organization estimates that 290,000 to 650,000 people die of flu-related causes every year worldwide. Nine in every ten deaths associated with influenza in the USA occur in adults older than 65 years. A study evaluated 90 individuals over 75 years that received 433 doses of influenza vaccine over at least four seasons. The goal was to determine the influence of age and sex on the effect of vaccination and levels of pre-existing immunity to influenza. The study compared the levels of pre- and post-vaccination immune response. The pre-vaccination immunity was constant with age in women but decreased significantly for men. Since the pre-vaccination titers were associated with post-vaccine results, pre-existing immunity in older adults is crucial. One of the ways to achieve it is a cumulative annual vaccination.
Source: nature.com, ncbi.com
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Dr. Ana Baroni MD. Ph.D.
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Ana has over 20 years of consultancy experience in longevity, regenerative and precision medicine. She has a multifaceted understanding of genomics, molecular biology, clinical biochemistry, nutrition, aging markers, hormones and physical training. This background allows her to bridge the gap between longevity basic sciences and evidence-based real interventions, putting them into the clinic, to enhance the healthy aging of people. She is co-founder of Origen.life, and Longevityzone. Board member at Breath of Health, BioOx and American Board of Clinical Nutrition. She is Director of International Medical Education of the American College of Integrative Medicine, Professor in IL3 Master of Longevity at Barcelona University and Professor of Nutrigenomics in Nutrition Grade in UNIR University.
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