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Pomegranates and citrus fruits could possibly promote healthy longevity
Daily supplementation of a citrus and pomegranate complex for four weeks improved physical fitness and psychological parameters in healthy older adults.
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Pomegranates and citrus fruits could possibly promote healthy longevity
Nutrition is recognized as an important modifiable risk factor with a significant impact on healthy aging. In this context, research shows that diets high in fruits, vegetables, and fish are associated with improved longevity. This is possibly attributed to polyphenols in the said dietary components, suggested to delay the negative consequences of aging and promote health.
Hesperidin and punicalagins are polyphenolic bioactive compounds found in citrus fruits and pomegranates. They have been suggested to have anti-inflammatory and antioxidant effects. Previous randomized controlled trials showed that polyphenol supplementation led to reduced malondialdehyde (MDA) (a product resulting from polyunsaturated fatty acids peroxidation). In addition, it led to an increase in Trolox (an antioxidant) equivalent antioxidative capacity (an assay that measures the antioxidant capacity of a substance in comparison to the standard, Trolox) and nitrate levels (a marker of endothelial function). However, the use of a citrus and pomegranate complex (CPC) in untrained older adults has not been investigated yet.
Ahles et al. sought to investigate whether four weeks of CPC supplementation improves physical fitness (measured through handgrip strength) in 36 healthy older adults aged 60–75 years. Secondary objectives were to assess the effects of CPC on mental health and systemic parameters of oxidative stress and endothelial function.
Results revealed that handgrip strength significantly improved after CPC supplementation compared to placebo. In addition, mental health parameters like thinking, learning, memory, and concentration were improved in the CPC group compared to placebo. Also, plasma MDA levels were reduced.
The investigators concluded that daily supplementation of CPC for four weeks improved physical fitness and psychological parameters in healthy older adults. Further investigation is needed to understand the value of CPC in enhancing the general health of the elderly population. Also, more research is required to understand the mechanism that led to such improvements.
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Pomegranates and citrus fruits could possibly promote healthy longevity
Nutrition is recognized as an important modifiable risk factor with a significant impact on healthy aging. In this context, research shows that diets high in fruits, vegetables, and fish are associated with improved longevity. This is possibly attributed to polyphenols in the said dietary components, suggested to delay the negative consequences of aging and promote health.
Hesperidin and punicalagins are polyphenolic bioactive compounds found in citrus fruits and pomegranates. They have been suggested to have anti-inflammatory and antioxidant effects. Previous randomized controlled trials showed that polyphenol supplementation led to reduced malondialdehyde (MDA) (a product resulting from polyunsaturated fatty acids peroxidation). In addition, it led to an increase in Trolox (an antioxidant) equivalent antioxidative capacity (an assay that measures the antioxidant capacity of a substance in comparison to the standard, Trolox) and nitrate levels (a marker of endothelial function). However, the use of a citrus and pomegranate complex (CPC) in untrained older adults has not been investigated yet.
Ahles et al. sought to investigate whether four weeks of CPC supplementation improves physical fitness (measured through handgrip strength) in 36 healthy older adults aged 60–75 years. Secondary objectives were to assess the effects of CPC on mental health and systemic parameters of oxidative stress and endothelial function.
Results revealed that handgrip strength significantly improved after CPC supplementation compared to placebo. In addition, mental health parameters like thinking, learning, memory, and concentration were improved in the CPC group compared to placebo. Also, plasma MDA levels were reduced.
The investigators concluded that daily supplementation of CPC for four weeks improved physical fitness and psychological parameters in healthy older adults. Further investigation is needed to understand the value of CPC in enhancing the general health of the elderly population. Also, more research is required to understand the mechanism that led to such improvements.
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Dr. Ana Baroni MD. Ph.D.
Scientific & Medical Advisor
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Ana has over 20 years of consultancy experience in longevity, regenerative and precision medicine. She has a multifaceted understanding of genomics, molecular biology, clinical biochemistry, nutrition, aging markers, hormones and physical training. This background allows her to bridge the gap between longevity basic sciences and evidence-based real interventions, putting them into the clinic, to enhance the healthy aging of people. She is co-founder of Origen.life, and Longevityzone. Board member at Breath of Health, BioOx and American Board of Clinical Nutrition. She is Director of International Medical Education of the American College of Integrative Medicine, Professor in IL3 Master of Longevity at Barcelona University and Professor of Nutrigenomics in Nutrition Grade in UNIR University.
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